In a medium saucepan combine preserves and half the vanilla. Stir in cherries and cook over medium heat, stirring occasionally, until mixture begins to bubble, 4 to 5 minutes.
Set pan in a bowl of ice water and stir often. Set aside, replacing ice if needed so cherry mixture stays cold.
Meanwhile, line a 9- x- 13-inch pan with a piece of foil extending over the ends. Arrange half crackers in pan, flat side up, in 3 rows of 5 squares with sides touching; freeze pan.
Process remaining vanilla, cream cheese, yogurt, sugar, and orange zest in a high-powered blender or food processor until smooth.
Freeze yogurt mixture in an ice cream maker according to package directions, about 25 minutes.
Spoon half frozen yogurt over graham crackers and gently spread to cover, using a flexible scraper or offset spatula.
Spoon berry mixture on top of yogurt. Dollop remaining frozen yogurt over berries. Pat yogurt smooth.
Draw a knife tip or toothpick through the layers all over until top looks swirled. Gently push remaining graham crackers into top.
Freeze, covered with plastic, until center is firm enough to cut, at least 5 hours. Grasping foil, lift sandwiches from pan, transfer to a work surface, and cut into squares, trimming edges.